Carboxylic acids and derivatives
![Alkali Scientific Deoxyribonucleic Acid Sodium Salt [DNA, Sodium Salt from Salmon Sperm], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661843.jpg-250.jpg)
Alkali Scientific Deoxyribonucleic Acid Sodium Salt [DNA, Sodium Salt from Salmon Sperm], 1 G
Deoxyribonucleic Acid (DNA) Sodium Salt from Salmon Sperm is an essential reagent in molecular biology, particularly for nucleic acid applications. This 1g quantity is ideal for large-scale procedures like DNA hybridization, PCR amplification, and cloning. The DNA sodium salt form is soluble in water, providing a reliable and easily prepared DNA source for experiments. It is frequently used in DNA fragmentation protocols, transfection procedures, and the preparation of DNA libraries. This reagent is indispensable for research in gene expression, gene manipulation, and molecular diagnostics, offering high-quality DNA for various analytical methods and laboratory assays.
Pfanstiehl Inc Streptozotocin (S-141) 100g - API, active pharmaceutical ingredient CAS: 18883-66-4
Streptozotocin (S-141) 100g - API, active pharmaceutical ingredient CAS: 18883-66-4
Apexbio Technology LLC Cefazolin (sodium salt) 27164-46-1 250mg
Cefazolin sodium salt (CAS 27164-46-1) is a semisynthetic antibiotic that inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins thereby blocking transpeptidation reactions essential for peptidoglycan formation In in vitro studies cefazolin sodium salt suppresses the proliferation of cultured osteoblast-like MG-63 cells exhibiting substantial cytotoxicity at concentrations of 10 000 g/ml precise IC50 values depend on cell type and experimental conditions Cefazolin sodium salt is commonly used in microbiology pharmacokinetic investigations and infection models particularly within studies of antimicrobial susceptibility and renal dysfunction
Medchemexpress LLC POPG (sodium salt) | 268550-95-4 | 99.2% | 1 ML
POPG sodium salt is a negatively charged phospholipid that influences the interactions of membrane proteins with other molecules by altering the charge characteristics of the lipid environment. It increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1 and can interact with the positive charge of peptides. This product can be utilized in Parkinson's disease research and in the preparation of nanoparticles for co-encapsulating and releasing hydrophilic peptide compounds.
- A negatively charged phospholipid
- Influences membrane protein interactions
- Increases affinity for activated NTS1
- Interacts with positive charge of peptides
- Applicable in Parkinson's disease research
- Used in nanoparticle preparation
- Enhances binding of PAP248-286 peptide
Apexbio Technology LLC WAY-100635 maleate salt 1092679-51-0 100mg
WAY-100635 maleate salt (CAS 1092679-51-0) is a selective antagonist of the serotonin 5-HT1A receptor subtype It demonstrates high potency with a reported pIC50 value of 8 87 and displays over 100-fold selectivity relative to other serotonin receptor isoforms and common neurotransmitter receptor classes Due to its specific interaction with 5-HT1A receptors WAY-100635 maleate is frequently applied in neuroscience research to elucidate serotonin-mediated pathways and associated physiological or behavioral responses
Medchemexpress LLC Enalapril (maleate) | 76095-16-4 | 99.95% | 250 MG
Enalapril maleate, also known as MK-421 maleate, is the active metabolite of enalapril and functions as an angiotensin-converting enzyme (ACE) inhibitor. Enalapril is a prodrug that is rapidly metabolized in the liver to enalaprilat following oral administration. It is a potent, competitive inhibitor of ACE, which is responsible for converting angiotensin I to angiotensin II, a key regulator of blood pressure. Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure. This product is for research use only.
- Harmful if swallowed.
- Causes skin and serious eye irritation.
- May cause respiratory irritation.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Keep container tightly sealed in a cool, well-ventilated area, away from moisture and direct sunlight.
- Wear protective gloves, clothing, eye protection, and face protection.
Apexbio Technology LLC WAY-100635 maleate salt 1092679-51-0 50mg
WAY-100635 maleate salt (CAS 1092679-51-0) is a selective antagonist of the serotonin 5-HT1A receptor subtype It demonstrates high potency with a reported pIC50 value of 8 87 and displays over 100-fold selectivity relative to other serotonin receptor isoforms and common neurotransmitter receptor classes Due to its specific interaction with 5-HT1A receptors WAY-100635 maleate is frequently applied in neuroscience research to elucidate serotonin-mediated pathways and associated physiological or behavioral responses
Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.84% | 391.42 | 1 ML
Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor. It has been shown to abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. This compound holds potential for research in Alzheimer's disease and congenital muscular dystrophy (CMD), and it also acts as an apoptosis inhibitor. Additionally, Omigapil maleate is a click chemistry reagent, possessing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active GAPDH nitrosylation inhibitor
- Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction abrogator
- Potential for Alzheimer's disease research
- Apoptosis inhibitor
- Can be used for congenital muscular dystrophy (CMD) research
- Click chemistry reagent with an Alkyne group for CuAAc reactions
Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 25 MG
Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It demonstrates inhibitory activity against Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit. This compound is intended for research use only.
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells.
- Reduces vessel area, length, and branching in a fibroblast/endothelial cell coculture model.
- Ablates experimental (VEGF-induced) angiogenesis in vivo.
- Inhibits endochondral ossification and corpora luteal development.
- Dose-dependently inhibits the growth of human tumor xenografts (colon, lung, prostate, breast, and ovary) in athymic mice.
- Shows a reduction in microvessel density within tumors, indicating vascular regression.
Medchemexpress LLC Tris (maleate) | 72200-76-1 | MFCD00082442 | 98.0% | 237.21 g/mol | C8H15NO7 | 10 G
Tris (maleate) is the maleate salt of tris(hydroxymethyl)aminomethane used as a buffering agent in biochemical and cell biology applications. It stabilizes pH in growth media, tissue preparations, and washing or diluent solutions, and is supplied as a highly soluble reagent to support reproducible experimental workflows.
- Buffered pH support for media and tissue preparations.
- Water-soluble; also soluble in DMSO with sonication if needed.
- High purity: 98.0%.
- Suitable for use as a diluent or washing buffer.
- Available in laboratory-scale package sizes such as 10 G.
TARGETMOL CHEMICALS INC CGP 3466B MALEATE 5MG
Also available in 2 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CGP 3466B maleate (Omigapil maleate) is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates A(beta)1-42-induced tau acetylation memory impairment and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD). purity: 98%
Apexbio Technology LLC L-693,403 maleate 207455-21-8 10mg
L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms